The Medical Advisor

Estimates suggest up to 20% of the general population experience chronic constipation, 1   characterized by hard, dry and difficult to pass stools, and/or having less than three bowel movements per week. Chronic constipation also accounts for at least 8 million annual doctor's visits in the U.S. 2 While temporary constipation can be the result of simply eating poorly for a day or two, chronic constipation has been linked to a number of other, more serious health problems, including diverticulitis, kidney disease, 3  colorectal and gastric cancer, 4  ulcerative colitis 5  and Parkinson's disease. 6 So, having regular bowel movements is not just a matter of comfort, it also has important health implications. Following are several of my top tips for getting and staying regular. 1. Stay Properly Hydrated Perhaps the most basic of all recommendations is to make sure you're drinking enough water each day. While using thirst as a guide to how much water you need is an obvio...

Lung cancer remains one of the most challenging and deadly malignancies worldwide, with limited effective treatment options for advanced stages despite advances in targeted therapies and immunotherapies. Patients with metastatic or treatment-resistant disease often face poor prognoses and unmet clinical needs, prompting exploration of novel and adjunctive therapeutic approaches. For patients with actionable mutations identified through molecular profiling, targeted therapies are the preferred treatment approach. In particular, for "PD-L1 High Non-Small Cell Lung Cancer", single-agent immunotherapy may be more effective and better tolerated than chemotherapy in selected patients. The preference for targeted treatments reflects their demonstrated efficacy in improving outcomes in these molecularly defined subgroups, underscoring the importance of comprehensive genomic profiling in guiding personalized therapy decisions. However, targeted agents are only applicable to small pati...