The Medical Advisor

Harvard medical student Nick Norwitz, who holds a doctorate in physiology from Oxford, recently embarked on a personal health experiment that captured public attention. In just one month, he ate 720 eggs—an average of 24 per day—and observed an 18 percent drop in his LDL cholesterol levels, commonly called “bad cholesterol.” He wasn’t advocating an extreme egg diet, which would not be a wise long-term way to eat. Nor was the science behind this experiment revolutionary—research has already shown that dietary cholesterol doesn’t significantly impact blood cholesterol for most people. Still, the story went viral. Many interpreted it as a green light to enjoy more eggs. However, the full takeaway of the experiment went beyond diet. Norwitz’s experiment highlights a growing trend in the scientific community, where individuals and researchers alike are turning to personalized, real-world experiments, often called N=1 studies, to answer pressing health questions. Eating two dozen eggs a day ...

In this article, we asked ChatGPT to provide a better solution for randomised controlled trials (RCTs). Here's what ChatGPT said : You're absolutely right—randomised controlled trials (RCTs), while considered the gold standard for evidence, are often costly, slow, and logistically challenging. Here are some pragmatic, more feasible alternatives or complementary approaches that can provide valuable evidence—especially in real-world settings or for repurposed/low-cost interventions: ✅ 1. Pragmatic Clinical Trials (PCTs) What : Conducted in real-world settings with broad patient inclusion criteria. Advantage : Less strict protocol than traditional RCTs, more generalisable, lower cost. Use Case : E.g., testing off-label or repurposed drugs like ivermectin or fenbendazole in actual outpatient settings. ...

Immune Systems Advisor Formerly The COVID Advisor — evidence-based analysis of long COVID, immune injury, and post-viral disease Review Article · Post-COVID & Post-Vaccine Syndrome A clinical review of the evidence base, dosing rationale, safety considerations, and monitoring strategy for the Base Spike Detox regimen in long COVID and post-vaccine injury syndromes — updated June 2026. Last Updated: June 2026 Authors: Editorial Team, Immune Systems Advisor Abstract Persistent SARS-CoV-2 spike protein — derived from infection, vaccination, or both — has been proposed as a pathophysiological driver of long COVID and post-vaccine inflammatory syndromes. Dr. Peter McCullough, a board-certified internist and cardiologist, has developed a three-agent over-the-counter regimen termed the "Base Spike Detox" that combines nattokinase (2,000 FU twice daily), ...