The Medical Advisor

Insulin resistance is one of the most overlooked factors influencing cancer outcomes. While oncology focuses on tumour genetics, drug targets, and immune checkpoints, a growing body of evidence suggests that the metabolic environment surrounding the tumour can quietly determine whether treatments work—or fail. This is not about replacing standard cancer therapy. It’s about understanding why the same drug can produce dramatically different outcomes in different patients, even with identical tumour markers. What Is Insulin Resistance (and Why It Matters in Cancer)? Insulin resistance occurs when cells no longer respond effectively to insulin, forcing the body to produce higher levels of insulin to maintain normal blood glucose. This leads to: Chronic hyperinsulinaemia Elevated IGF-1 signalling Increased inflammation Altered immune cell function All of these are biologically relevant to cancer. Cancer does not grow in isolation. It grows inside a metabolic system. How Insulin Resistance ...

Ivermectin Resources I have seen tremendous demand for some sort of initial guidance “WHERE TO START” with High Dose Ivermectin for CANCER. Editor's Note: Dr Makis proposes four distinct cancer protocols for using Ivermectin in cancer treatment, specifically for patients who have developed turbo cancer or aggressive cancers. These protocols, referred to as the “Dr. Makis Ivermectin Cancer Protocols,” are categorized based on dosage and the severity of the cancer. Updated version I have an article and a video that go into depth: June 10, 2024 - "15 minutes with Dr.Makis" - Episode 018: High Dose Ivermectin and Cancer .  2025 - 2026 studies on ivermectin for cancer Clinical Yuan Yuan et al (Cedars-Sinai Medical Center) - A phase I/II study evaluating the safety and efficacy of ivermectin in combination with balstilimab in patients with metastatic triple negative breast cancer (ASCO 2025) Yuwen et al -  A Review of Ivermectin Use in Cancer Patients: Is it Time to Repurpose t...

Fenbendazole and ivermectin, both antiparasitic drugs, have shown promising potential in cancer treatment. Fenbendazole is being studied for its ability to disrupt energy production in cancer cells, effectively hindering their growth. Ivermectin , on the other hand, has been explored in combination with checkpoint inhibitors to boost the immune system's response to tumors—especially in challenging cases like triple-negative breast cancer. Table of Contents Introduction What is Ivermectin What is Fenbendazole Chemical Structure and Mechanism of Action Comparing the Spectrum of ‍Activity The Role of Ivermectin in Cancer Symptoms The Role of Fenbendazole in Cancer Symptoms Safety ⁣Profile and Side Effects: Assessing Risks and Tolerability Should You Use Ivermectin or Fenbendazole for Cancer? Ivermectin and Fenbendazole for Cancer Route of Administration and Dosage Forms Ivermectin dosage for Cancer Fenbendazole dosage for Cancer Cost-Effectiveness and Availability: Evaluating Economi...